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Recombinant SARS-CoV-2 Spike RBD Protein (bs-46009P)

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说明书: 下载
100ug/3600.00元
500ug/12800.00元
大包装/询价
产品编号 bs-46009P
英文名称 Recombinant SARS-CoV-2 Spike RBD Protein
中文名称 重组SARS冠状病毒2 Spike RBD蛋白
别    名 coronavirus spike Protein, 2019-nCoV; cov spike Protein, 2019-nCoV; novel coronavirus RBD Protein, 2019-nCoV; novel coronavirus s1 Protein, 2019-nCoV; novel coronavirus spike Protein, 2019-nCoV; RBD Protein, 2019-nCoV; S1 Protein, 2019-nCoV; pike RBD Protein, 2019-nCoV  
Specific References  (1)     |     bs-46009P has been referenced in 1 publications.
[IF=] Curreli F et al. Stapled Peptides Based on Human Angiotensin-Converting Enzyme 2 (ACE2) Potently Inhibit SARS-CoV-2 Infection In VitromBio.2020 Dec 11;11(6):e02451-20.  other ;  
性    状 lyophilized powder
种属同源 SARS-CoV-2
序    列 It contains Arg319-Asn532
产品来源 基因工程表达
分    类 重组蛋白
纯化方法 亲和层析
产品应用 Immunology research 
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
产品介绍 The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.

SWISS:
P0DTC2

Gene ID:
43740568

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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