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Recombinant SARS-CoV-2 (2019-nCoV) Spike protein fragment 2 protein, N-His-Tag (bs-46108P)

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说明书: 100ug  500ug  1mg
100ug/4800.00元
500ug/15800.00元
1mg/30000.00元
大包装/询价
产品编号 bs-46108P
英文名称 Recombinant SARS-CoV-2 (2019-nCoV) Spike protein fragment 2 protein, N-His-Tag
中文名称 重组SARS冠状病毒2Spike 蛋白
别    名 Spike glycoprotein;Spike protein.  
分 子 量 19.69kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
种属同源 SARS-CoV-2
序    列 Tyr1047-Gln1201
产品来源 基因工程表达
分    类 重组蛋白
纯化方法 亲和层析
产品应用 Immunology research 
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
产品介绍 Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

SWISS:
P0DTC2

Gene ID:
43740568

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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