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说明书: 50ul  100ul  200ul
50ul/1138.00元
100ul/1880.00元
200ul/2900.00元
大包装/询价
产品编号 bs-16064R
英文名称 FCRL1
中文名称 CD307a抗体
别    名 CD307a; Fc receptor homolog 1; Fc receptor like protein 1; Fc receptor-like protein 1; FcR like protein 1; FcR-like protein 1; FCRH 1; FcRH1; FCRL 1; FcRL1; FCRL1_HUMAN; hIFGP 1; hIFGP1; IFGP 1; IFGP family protein 1; IFGP1; Immune receptor translocation associated protein 5; Immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42; IRTA 5; IRTA5; RP11 367J7.7.  
研究领域 细胞生物  免疫学  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FCRL1:251-350/429 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Function:
May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B-cells (at protein level).

Post-translational modifications:
Phosphorylated on tyrosines upon activation.

Similarity:
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:
Q96LA6

Gene ID:
115350

Database links:

Entrez Gene: 115350 Human

Omim: 606508 Human

SwissProt: Q96LA6 Human

Unigene: 656112 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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